.navbar .breadcrumb {
  margin-bottom: 0px;
  background: none; }

.high-quality {
  border-left: 5px solid green; }

.medium-quality {
  border-left: 5px solid yellow; }

.low-quality {
  border-left: 5px solid red; }

.no-quality {
  border-left: 5px solid lightgrey; }

.guide-quality {
  box-sizing: border-box;
  width: 100%;
  padding-top: 10px;
  padding-bottom: 10px;
  margin-top: 10px;
  margin-bottom: 10px; }
  .guide-quality > div {
    padding-left: 10px; }

.annotation {
  opacity: 0.4; }

.spacer-v-container {
  margin-left: 20px; }

.col-tables-area {
  white-space: nowrap; }
  .col-tables-area .col {
    box-sizing: border-box;
    position: relative;
    height: 100%;
    display: inline-block;
    vertical-align: text-top; }
    .col-tables-area .col.left {
      width: 400px;
      padding-left: 20px;
      z-index: 1; }
    .col-tables-area .col.right {
      width: 100%;
      margin-left: -400px;
      padding-right: 20px;
      padding-left: 420px;
      z-index: 0; }

.job-list-v {
  box-sizing: border-box;
  min-height: 600px; }
  .job-list-v table {
    width: 100%;
    margin-right: 10px;
    border-right: 1px dotted rgba(0, 0, 0, 0.1); }
    .job-list-v table tr.list-row {
      border-bottom-width: 0px;
      border-left-width: 5px;
      border-top-width: 0px; }
      .job-list-v table tr.list-row th, .job-list-v table tr.list-row td {
        padding-left: 10px; }
        .job-list-v table tr.list-row th:not(:last-child), .job-list-v table tr.list-row td:not(:last-child) {
          padding-right: 10px; }
      .job-list-v table tr.list-row th {
        text-align: center; }
    .job-list-v table tr.spacer-list-v.active {
      border-right: 1px solid black;
      background-color: rgba(0, 0, 0, 0.05); }
    .job-list-v table tr.nickase-list-v {
      cursor: pointer; }
      .job-list-v table tr.nickase-list-v:not(.active) {
        opacity: .25; }
      .job-list-v table tr.nickase-list-v.active {
        border-right: 1px solid black;
        background-color: rgba(0, 0, 0, 0.05); }

.qscore {
  font-weight: bold;
  color: blue; }

.spacer-h-v-container .info {
  display: inline-block; }
  .spacer-h-v-container .info dl.header {
    margin-top: 8px;
    margin-bottom: 8px; }
  .spacer-h-v-container .info dl {
    margin-top: 0px;
    margin-bottom: 0px;
    display: inline-block;
    box-sizing: border-box; }
    .spacer-h-v-container .info dl dt, .spacer-h-v-container .info dl dd {
      display: inline; }
    .spacer-h-v-container .info dl dt:not(:first-child) {
      margin-left: 15px;
      font-weight: bold; }
    .spacer-h-v-container .info dl dd {
      margin-left: 2px; }
.spacer-h-v-container .spacer-h-view .table-type-selection {
  display: block; }
  .spacer-h-v-container .spacer-h-view .table-type-selection .hspace-80 {
    height: 0px;
    vertical-align: middle;
    margin-left: 20px;
    margin-right: 10px;
    border-top: 1px dotted rgba(0, 0, 0, 0.25);
    width: 140px;
    display: inline-block; }
  .spacer-h-v-container .spacer-h-view .table-type-selection input {
    margin-top: -1px;
    margin-right: 10px;
    margin-left: 10px; }
.spacer-h-v-container .spacer-h-view .hits {
  margin-top: 20px; }
  .spacer-h-v-container .spacer-h-view .hits.top table.gene {
    display: none; }
  .spacer-h-v-container .spacer-h-view .hits.gene table.top {
    display: none; }
  .spacer-h-v-container .spacer-h-view .hits table {
    width: 100%; }
    .spacer-h-v-container .spacer-h-view .hits table th, .spacer-h-v-container .spacer-h-view .hits table td {
      padding-right: 10px; }
      .spacer-h-v-container .spacer-h-view .hits table th:nth-child(even), .spacer-h-v-container .spacer-h-view .hits table td:nth-child(even) {
        background-color: rgba(0, 0, 0, 0.02); }
      .spacer-h-v-container .spacer-h-view .hits table th:not(:first-child), .spacer-h-v-container .spacer-h-view .hits table td:not(:first-child) {
        padding-left: 10px; }
    .spacer-h-v-container .spacer-h-view .hits table th {
      text-align: center; }
    .spacer-h-v-container .spacer-h-view .hits table td {
      font-family: courier;
      white-space: nowrap; }
      .spacer-h-v-container .spacer-h-view .hits table td.sequence, .spacer-h-v-container .spacer-h-view .hits table td.score, .spacer-h-v-container .spacer-h-view .hits table td.locus, .spacer-h-v-container .spacer-h-view .hits table td.gene {
        text-align: center; }

.job-v .job-title {
  line-height: 32px;
  position: relative;
  display: inline-block; }
.job-v .show-info {
  background-image: url(/img/info.svg);
  width: 32px;
  height: 32px;
  margin-bottom: -6px;
  position: absolute;
  left: 0px;
  margin-left: -48px;
  margin-top: -16px;
  top: 50%;
  display: inline-block;
  opacity: .3;
  background-size: 100%; }
  .job-v .show-info:hover {
    opacity: .9; }
.job-v .svg-container {
  margin-top: 10px;
  margin-bottom: 20px;
  padding-bottom: 20px;
  display: block;
  width: 800px;
  margin-left: auto;
  margin-right: auto; }
.job-v .job-description {
  position: fixed;
  right: 0px;
  left: 0px;
  margin-left: 100px;
  margin-right: 100px;
  background-color: white;
  border: 5px solid black;
  border-radius: 12px;
  padding: 10px;
  box-shadow: 5px 5px 20px -10px; }
  .job-v .job-description dl {
    margin-bottom: 0px;
    margin-top: 0px; }
  .job-v .job-description dd, .job-v .job-description dt {
    display: inline-block; }
  .job-v .job-description dt {
    margin-top: 5px;
    width: 120px;
    white-space: nowrap; }
  .job-v .job-description dd {
    max-width: 600px;
    margin-left: 10px; }
    .job-v .job-description dd.seq {
      color: rgba(0, 0, 0, 0.25);
      vertical-align: text-top;
      line-height: 25px; }

.job-link-v a > *:second-child {
  display: inline-block;
  width: 75px; }
.job-link-v a .name {
  font-weight: bold; }
.job-link-v a .unstarted {
  color: red; }
.job-link-v a .started {
  color: green; }

.file-list-v {
  min-height: 10px;
  width: 100%;
  box-sizing: border-box;
  padding-top: 15px;
  padding-bottom: 15px;
  border-top: 1px rgba(0, 0, 0, 0.05) solid;
  border-bottom: 1px rgba(0, 0, 0, 0.05) solid;
  margin-top: 15px;
  margin-bottom: 10px; }
  .file-list-v .files {
    margin-left: 20px; }
    .file-list-v .files .file-v {
      margin-left: 10px; }
      .file-list-v .files .file-v:not(.ready) {
        pointer-events: none; }
        .file-list-v .files .file-v:not(.ready) a {
          color: rgba(0, 0, 0, 0.3); }

.cards .card {
  vertical-align: top;
  width: 200px;
  min-height: 200px;
  position: relative;
  display: inline-block;
  border: 1px solid black;
  margin: 25px;
  padding: 10px; }
  .cards .card .header {
    position: absolute;
    bottom: 100%;
    left: 0px; }
  .cards .card .footer {
    margin-top: 0px;
    position: absolute;
    top: 100%;
    left: 0px;
    border-top: none; }
  .cards .card .covering-link {
    position: absolute;
    top: 0px;
    left: 0px;
    right: 0px;
    bottom: 0px; }

.tabs-label {
  position: absolute;
  top: 11px;
  background-color: white;
  padding-right: 20px; }

.nav-tabs.crispr-tabs {
  margin-top: 30px;
  margin-bottom: 14px;
  position: relative; }

.tab-header-annotation {
  opacity: .5; }

.header-oneline > * {
  display: inline-block; }

.footer {
  margin-top: 100px;
  border-top: 1px solid #efefef;
  padding-top: 1em;
  text-align: center; }

.inline {
  display: inline; }

.full-width {
  box-sizing: border-box;
  position: relative;
  width: 100%; }

body.submit, body.batch body.about, body.readout, body.nickase, body.job, body.downloads {
  padding-left: 75px;
  padding-right: 75px; }
  body.submit > .header, body.batch body.about > .header, body.readout > .header, body.nickase > .header, body.job > .header, body.downloads > .header {
    margin-left: -75px;
    margin-right: -75px; }
body .nav-tabs {
  margin-top: -36px;
  padding-right: 20px;
  border-bottom: 1px solid #eeeeee; }
  body .nav-tabs li {
    border-color: #eee;
    float: right; }
    body .nav-tabs li > a {
      padding-top: 6px;
      padding-bottom: 6px; }
body .disabled {
  opacity: .4;
  color: black; }

.navbar.navbar.navbar a, .navbar.navbar.navbar .brand {
  padding-top: 5px;
  padding-bottom: 5px; }

body.submit .navbar > * {
  padding-left: 75px;
  padding-right: 75px; }
body .navbar {
  margin-bottom: 0px; }
  body .navbar .brand {
    opacity: .9;
    font-family: "Alegreya SC", serif; }
  body .navbar > * {
    padding-left: 10px;
    padding-right: 10px;
    background-color: #fafafa;
    -webkit-font-smoothing: antialiased;
    border-radius: 0px;
    border-bottom: 1px solid #dddddd; }

.alert.header {
  margin-bottom: 0px; }

.alert .content {
  max-width: 500px;
  margin: 0 auto; }
  .alert .content.showing-less .text-fixed-width-content {
    max-width: 400px;
    white-space: nowrap;
    overflow: hidden;
    text-overflow: ellipsis;
    display: inline-block;
    opacity: .7; }
  .alert .content > * {
    vertical-align: text-bottom; }

.med-left-margin {
  margin-left: 20px; }

.med-top-margin {
  margin-top: 20px; }

.small-left-margin {
  margin-left: 1em; }

.unselectable {
  -moz-user-select: -moz-none;
  -khtml-user-select: none;
  -webkit-user-select: none;
  user-select: none; }

.disabled {
  color: lightgray;
  cursor: not-allowed; }

.sequence {
  font-family: courier; }

.v-middle {
  vertical-align: middle; }

.valid {
  position: fixed;
  width: 200px;
  right: 0px;
  background-color: #FEFEFE;
  border: 1px solid lightgrey;
  padding: 20px;
  margin: 25px;
  bottom: 0px; }
  .valid .dna {
    word-break: break-all; }
  .valid li {
    margin-top: 10px; }

.showing-less > .more {
  display: none; }

.showing-more > .less {
  display: none; }

body .navbar li > a, body .navbar .brand {
  color: black; }

.section {
  padding: .5em;
  margin: 1em; }

.section.bad {
  border: 1px solid rgba(255, 0, 0, 0.3); }
  .section.bad .header {
    color: red; }

.section.good {
  border: 1px solid rgba(0, 255, 0, 0.3); }
  .section.good .header {
    color: green; }

.inactive {
  opacity: .25;
  pointer-events: none; }

#navparent {
  width: 0px;
  height: 0px;
  display: inline-block;
  position: fixed;
  left: 0px;
  top: 50%;
  margin-top: -56px; }

.bs-docs-sidenav {
  width: 128px;
  margin: 0px 0 0;
  padding: 0;
  background-color: #fff;
  -webkit-border-radius: 6px;
  -moz-border-radius: 6px;
  border-radius: 6px;
  -webkit-box-shadow: 0 1px 4px rgba(0, 0, 0, 0.065);
  -moz-box-shadow: 0 1px 4px rgba(0, 0, 0, 0.065);
  box-shadow: 0 1px 4px rgba(0, 0, 0, 0.065); }

.bs-docs-sidenav > li > a {
  display: block;
  width: 90px 9;
  margin: 0 0 -1px;
  padding: 8px 14px;
  border: 1px solid #e5e5e5; }

.bs-docs-sidenav .icon-chevron-right {
  float: right;
  margin-top: 2px;
  margin-right: -6px;
  opacity: .25; }

.bs-docs-sidenav .active .icon-chevron-right, .bs-docs-sidenav .active a:hover .icon-chevron-right {
  background-image: url(../img/glyphicons-halflings-white.png);
  opacity: 1; }

.bs-docs-sidenav > .active > a {
  position: relative;
  z-index: 2;
  padding: 9px 15px;
  border: 0;
  text-shadow: 0 1px 0 rgba(0, 0, 0, 0.15);
  -webkit-box-shadow: inset 1px 0 0 rgba(0, 0, 0, 0.1), inset -1px 0 0 rgba(0, 0, 0, 0.1);
  -moz-box-shadow: inset 1px 0 0 rgba(0, 0, 0, 0.1), inset -1px 0 0 rgba(0, 0, 0, 0.1);
  box-shadow: inset 1px 0 0 rgba(0, 0, 0, 0.1), inset -1px 0 0 rgba(0, 0, 0, 0.1); }

a {
  cursor: pointer; }

body.nickase #nickase-container {
  padding-top: 35px; }
body.nickase .page-header:not(h4) {
  margin-top: 0px; }
body.nickase .pane1 {
  width: 100%;
  display: inline-block; }
  body.nickase .pane1 label {
    text-overflow: ellipsis;
    overflow: hidden;
    white-space: nowrap; }
  body.nickase .pane1 .radio {
    padding-left: 25px; }
  body.nickase .pane1 .main.graphics {
    overflow: hidden; }
body.nickase .pane2 {
  z-index: 2;
  display: inline-block; }
  body.nickase .pane2 .nicks-list {
    position: relative;
    max-height: 300px;
    padding-top: 5px;
    max-height: 351px;
    overflow-x: visible;
    overflow-y: auto; }
body.nickase .pane3 {
  vertical-align: top;
  padding-top: 30px; }
body.nickase .pane.left {
  position: relative;
  width: 270px;
  display: inline-block;
  vertical-align: top; }
body.nickase .pane.right {
  display: inline-block;
  margin-left: 25px;
  margin-left: -270px;
  padding-left: 290px;
  width: 100%;
  box-sizing: border-box;
  position: relative; }
body.nickase .panes.top {
  position: relative;
  white-space: nowrap; }
  body.nickase .panes.top > * {
    white-space: normal; }
body.nickase table {
  white-space: nowrap; }
body.nickase .nickase-tl-options {
  width: 100%;
  margin-bottom: 5px;
  white-space: normal; }
  body.nickase .nickase-tl-options form {
    margin-left: 20px;
    margin-bottom: 0px; }
    body.nickase .nickase-tl-options form .control-group {
      margin-bottom: 0px; }
  body.nickase .nickase-tl-options .controls {
    margin-left: 10px; }
  body.nickase .nickase-tl-options .full-width-bottom {
    position: relative;
    width: 100%; }
    body.nickase .nickase-tl-options .full-width-bottom .right {
      position: absolute;
      right: 0px; }
body.nickase .hover-helper {
  margin-left: 33%;
  position: relative;
  color: rgba(0, 0, 0, 0.5);
  vertical-align: text-bottom; }

.scores-explanation {
  padding-top: 10px;
  white-space: normal; }

.graphics {
  height: 300px;
  display: block;
  position: relative;
  width: 100%;
  -webkit-touch-callout: none;
  -webkit-user-select: none;
  -khtml-user-select: none;
  -moz-user-select: none;
  -ms-user-select: none;
  user-select: none;
  border: lightgrey solid 1px; }
  .graphics.locked .svg-container {
    pointer-events: none; }

body.locked .click-grabber {
  display: block;
  pointer-events: auto; }

.click-grabber {
  pointer-events: none;
  cursor: pointer;
  position: absolute;
  display: none;
  z-index: 10;
  top: 0px;
  right: 0px;
  left: 0px;
  bottom: 0px; }

.nick-active-highlight {
  opacity: 0; }
  .nick-active-highlight[active=true] {
    opacity: .05; }

.nick-svg-view-group:not([active=true]) > text {
  opacity: 0; }
.nick-svg-view-group:not([active=true]) > line {
  opacity: .1; }
.nick-svg-view-group[active=true] {
  opacity: .9; }

.nickase-detail-view .page-header {
  padding-bottom: 3px; }
.nickase-detail-view .full-width.header {
  width: 100%;
  margin-bottom: 20px; }
  .nickase-detail-view .full-width.header > * {
    vertical-align: text-bottom;
    margin-top: 0px;
    margin-bottom: 0px; }
  .nickase-detail-view .full-width.header .nickase-detail-title {
    display: inline-block; }
.nickase-detail-view .cards .card {
  padding-top: 50px; }
  .nickase-detail-view .cards .card.sequence-section {
    padding-top: 10px; }
    .nickase-detail-view .cards .card.sequence-section .sequence {
      color: rgba(0, 0, 0, 0.25); }
      .nickase-detail-view .cards .card.sequence-section .sequence.selected {
        color: black; }
  .nickase-detail-view .cards .card .qbox {
    position: absolute;
    top: 0px;
    left: 0px;
    right: 0px;
    height: 40px;
    padding-top: 5px;
    padding-bottom: 5px;
    padding-right: 5px;
    border-bottom: 1px dotted black; }
    .nickase-detail-view .cards .card .qbox > span {
      display: block;
      line-height: 40px;
      color: white;
      text-align: right;
      font-size: 300%; }
  .nickase-detail-view .cards .card.high {
    background-color: rgba(48, 80, 48, 0.05); }
    .nickase-detail-view .cards .card.high .qbox {
      background-color: rgba(16, 112, 16, 0.25); }
  .nickase-detail-view .cards .card.medium {
    background-color: rgba(159, 159, 96, 0.05); }
    .nickase-detail-view .cards .card.medium .qbox {
      background-color: rgba(223, 223, 32, 0.25); }
  .nickase-detail-view .cards .card.bad {
    background-color: rgba(159, 96, 96, 0.05); }
    .nickase-detail-view .cards .card.bad .qbox {
      background-color: rgba(223, 32, 32, 0.25); }
  .nickase-detail-view .cards .card.sequence-section .sequence {
    word-break: break-all; }
.nickase-detail-view .spacer {
  display: inline-block;
  width: auto; }
  .nickase-detail-view .spacer dd {
    margin-left: 10px; }
.nickase-detail-view .details-svg-container {
  margin-top: 20px;
  margin-bottom: 30px; }
.nickase-detail-view .sequence-details-container {
  margin-bottom: 25px; }
.nickase-detail-view .sequence {
  font-family: courier; }

body.nickase .nicks-list {
  border-bottom: 1px dotted rgba(0, 0, 0, 0.1); }

.job-list-v.nicks-list .header {
  padding: 1em;
  padding-bottom: 0em;
  font-style: italic; }

.nickase.list-row:not(.included) {
  display: none; }

#readout {
  margin-top: 35px; }

.left {
  text-align: left; }

.center {
  text-align: center; }

th {
  padding-left: 5px;
  padding-right: 5px; }

svg {
  font-family: courier;
  font-size: 10px; }

.dna {
  font-family: courier; }

.locus {
  font-family: courier; }

.nrg {
  color: green;
  font-weight: bold; }

.occupied {
  color: rgba(0, 0, 0, 0.75);
  text-decoration: underline; }

.break-all {
  word-break: break-all; }

.hover {
  display: none; }

#sequence_submission_area {
  min-width: 325px; }

#submit {
  margin-top: 50px; }
  #submit .tab-content {
    overflow: visible; }
    #submit .tab-content .tab-pane {
      padding-top: 80px;
      max-width: 600px;
      margin-right: auto;
      margin-left: auto; }
      #submit .tab-content .tab-pane .header-description {
        margin-top: -60px;
        position: absolute;
        text-align: center;
        left: 0px;
        right: 0px;
        color: #000;
        opacity: .5;
        font-size: 100%; }
  #submit form.submitted {
    cursor: wait; }
    #submit form.submitted .submit-group input {
      pointer-events: none;
      opacity: .5; }
    #submit form.submitted input[type='file'] {
      width: 95px; }

body.job #job-container {
  margin-top: 35px; }
body.job .job-page-pages-view {
  margin-bottom: 25px; }
body.job .job-page-status-view {
  margin-bottom: 35px; }
  body.job .job-page-status-view .status {
    box-sizing: border-box;
    font-family: courier;
    text-align: center;
    overflow: hidden;
    position: relative;
    width: 100%;
    margin-top: 0px;
    margin-bottom: 0px; }
    body.job .job-page-status-view .status .progress {
      margin-top: 10px;
      margin-bottom: 10px; }
    body.job .job-page-status-view .status.done .progress {
      height: 1px;
      opacity: .5;
      transition: height 1s, opacity 0.5s; }
body.job .right {
  position: absolute;
  right: 0px; }
body.job .cards {
  padding-left: 25px;
  padding-top: 50px;
  padding-bottom: 50px; }
  body.job .cards .card .footer {
    padding-top: 4px;
    width: 100%;
    text-align: left; }
  body.job .cards #email-complete {
    margin: 0px; }
  body.job .cards .card {
    min-height: 0px;
    height: 150px;
    width: 150px;
    margin: 35px;
    border-color: lightgray; }
    body.job .cards .card:first-child {
      margin-left: 15px; }
    body.job .cards .card .background {
      background-repeat: no-repeat;
      background-position: center;
      opacity: .7;
      position: absolute;
      left: 0px;
      top: 0px;
      right: 0px;
      bottom: 0px; }
    body.job .cards .card:hover {
      border-color: black; }
      body.job .cards .card:hover .background {
        opacity: 1; }
    body.job .cards .card.nickase .background {
      background-image: url("/img/nickase-preview.svg"); }
    body.job .cards .card.guides .background {
      background-image: url("/img/crispr-logo.jpg"); }
body.job:not(.done) .nickase {
  cursor: wait;
  opacity: .25; }
  body.job:not(.done) .nickase > * {
    pointer-events: none; }
body.job:not(.done) .download-container {
  cursor: wait; }
  body.job:not(.done) .download-container a {
    color: rgba(0, 0, 0, 0.5);
    pointer-events: none; }
body.job.done .wait-for-nickase {
  display: none; }
body.job h3 {
  margin-top: 20px;
  margin-bottom: 0px; }

body.downloads #downloads-container {
  padding-top: 35px; }